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ERα-targeted endocrine therapy, resistance and the role of GPER

Endocrine therapy is an effective option for the treatment of estrogen receptor alpha (ERα)-positive breast cancers. Unfortunately, a large fraction of women relapse with endocrine-resistant tumors. The presence of constitutively active ERα mutants, found in a subset of relapse tumors, is thought to...

詳細記述

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書誌詳細
出版年:Steroids
主要な著者: Pepermans, Richard A., Prossnitz, Eric R.
フォーマット: Artigo
言語:Inglês
出版事項: 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6859199/
https://ncbi.nlm.nih.gov/pubmed/31518595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.steroids.2019.108493
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