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Targeting opioid dysregulation in depression for the development of novel therapeutics

Since the serendipitous discovery of the first class of modern antidepressants in the 1950’s, all pharmacotherapies approved by the Food and Drug Administration for major depressive disorder (MDD) have shared a common mechanism of action, increased monoaminergic neurotransmission. Despite the widesp...

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Vydáno v:Pharmacol Ther
Hlavní autoři: Browne, Caroline A, Lucki, Irwin
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6859062/
https://ncbi.nlm.nih.gov/pubmed/31051197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pharmthera.2019.04.009
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