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Targeting opioid dysregulation in depression for the development of novel therapeutics

Since the serendipitous discovery of the first class of modern antidepressants in the 1950’s, all pharmacotherapies approved by the Food and Drug Administration for major depressive disorder (MDD) have shared a common mechanism of action, increased monoaminergic neurotransmission. Despite the widesp...

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Bibliografiske detaljer
Udgivet i:Pharmacol Ther
Main Authors: Browne, Caroline A, Lucki, Irwin
Format: Artigo
Sprog:Inglês
Udgivet: 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6859062/
https://ncbi.nlm.nih.gov/pubmed/31051197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pharmthera.2019.04.009
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