Tumor Downstaging as an Intermediate Endpoint to Assess the Activity of Neoadjuvant Systemic Therapy in Patients With Muscle-Invasive Bladder Cancer

BACKGROUND: Achieving a pathologic complete response (pCR) with neoadjuvant chemotherapy (NAC) in patients with muscle-invasive bladder cancer (MIBC) has been associated with improved overall survival (OS). This study was aimed at evaluating the impact of pathologic downstaging (pDS; ie, a pT stage...

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Publicat a:Cancer
Autors principals: Martini, Alberto, Jia, Rachel, Ferket, Bart S., Waingankar, Nikhil, Plimack, Elizabeth R., Crabb, Simon J., Harshman, Lauren C., Yu, Evan Y., Powles, Thomas, Rosenberg, Jonathan E., Pal, Sumanta K., Vaishampayan, Ulka N., Necchi, Andrea, Wiklund, N. Peter, Mehrazin, Reza, Mazumdar, Madhu, Sfakianos, John P., Galsky, Matthew D.
Format: Artigo
Idioma:Inglês
Publicat: 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6859003/
https://ncbi.nlm.nih.gov/pubmed/31150110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.32169
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