Vacuolar ATPase as a potential therapeutic target and mediator of treatment resistance in cancer

Tekijä Whitton, Bradleigh, Okamoto, Haruko, Packham, Graham, Crabb, Simon J.
Julkaisussa Cancer Med (2018)

V-ATPase inhibition decreases mutant androgen receptor activity in castrate-resistant prostate cancer

Tekijä Whitton, Bradleigh, Okamoto, Haruko, Rose-Zerilli, Matthew, Packham, Graham, Crabb, Simon J.
Julkaisussa Mol Cancer Ther (2021)

Epigenetic modulators as therapeutic targets in prostate cancer

Tekijä Graça, Inês, Pereira-Silva, Eva, Henrique, Rui, Packham, Graham, Crabb, Simon J., Jerónimo, Carmen
Julkaisussa Clin Epigenetics (2016)

Can clinically relevant prognostic subsets of breast cancer patients with four or more involved axillary lymph nodes be identified through immunohistochemical biomarkers? A tissue...

Tekijä Crabb, Simon J, Bajdik, Chris D, Leung, Samuel, Speers, Caroline H, Kennecke, Hagen, Huntsman, David G, Gelmon, Karen A
Julkaistu 2008

Thioflavin S (NSC71948) Interferes with Bcl-2-Associated Athanogene (BAG-1)-Mediated Protein-Protein Interactions

Tekijä Sharp, Adam, Crabb, Simon J., Johnson, Peter W. M., Hague, Angela, Cutress, Ramsey, Townsend, Paul A., Ganesan, A., Packham, Graham
Julkaistu 2009

ProCAID: a phase I clinical trial to combine the AKT inhibitor AZD5363 with docetaxel and prednisolone chemotherapy for metastatic castration resistant prostate cancer

Tekijä Crabb, Simon J., Birtle, Alison J., Martin, Karen, Downs, Nichola, Ratcliffe, Ian, Maishman, Tom, Ellis, Mary, Griffiths, Gareth, Thompson, Stuart, Ksiazek, Lidia, Khoo, Vincent, Jones, Robert J.
Julkaisussa Invest New Drugs (2017)

The Prognostic Role of the Change in Neutrophil-to-Lymphocyte Ratio During Neoadjuvant Chemotherapy in Patients with Muscle-Invasive Bladder Cancer: A Retrospective, Multi-Institut...

Tekijä Kaiser, Jeenan, Li, Haocheng, North, Scott A., Leibowitz-Amit, Raya, Seah, Jo-An, Morshed, Nisha, Chau, Caroline, Lee-Ying, Richard, Heng, Daniel Y.C., Sridhar, Srikala, Crabb, Simon J., Alimohamed, Nimira S.
Julkaisussa Bladder Cancer (2018)

LSD1 inhibition attenuates androgen receptor V7 splice variant activation in castration resistant prostate cancer models

Tekijä Regufe da Mota, Sergio, Bailey, Sarah, Strivens, Rosemary A., Hayden, Annette L., Douglas, Leon R., Duriez, Patrick J., Borrello, M. Teresa, Benelkebir, Hanae, Ganesan, A., Packham, Graham, Crabb, Simon J.
Julkaisussa Cancer Cell Int (2018)

Persistent Neutrophil to Lymphocyte Ratio >3 during Treatment with Enzalutamide and Clinical Outcome in Patients with Castration-Resistant Prostate Cancer

Tekijä Conteduca, Vincenza, Crabb, Simon J., Jones, Robert J., Caffo, Orazio, Elliott, Tony, Scarpi, Emanuela, Fabbri, Paolo, Derosa, Lisa, Massari, Francesco, Numico, Gianmauro, Zarif, Sunnya, Hanna, Catherine, Maines, Francesca, Joyce, Helen, Lolli, Cristian, De Giorgi, Ugo
Julkaisussa PLoS One (2016)

Systemic immune-inflammation index predicts the clinical outcome in patients with metastatic renal cell cancer treated with sunitinib

Tekijä Lolli, Cristian, Basso, Umberto, Derosa, Lisa, Scarpi, Emanuela, Sava, Teodoro, Santoni, Matteo, Crabb, Simon J., Massari, Francesco, Aieta, Michele, Conteduca, Vincenza, Maruzzo, Marco, La Russa, Francesca, Wheater, Matthew, Berardi, Rossana, Galli, Luca, De Giorgi, Ugo
Julkaisussa Oncotarget (2016)

Phase I trial of DNA methyltransferase inhibitor guadecitabine combined with cisplatin and gemcitabine for solid malignancies including urothelial carcinoma (SPIRE)

Tekijä Crabb, Simon J., Danson, Sarah, Catto, James W.F., Hussain, Syed, Chan, Danna, Dunkley, Denise, Downs, Nichola, Marwood, Ellice, Day, Laura, Saunders, Geoff, Light, Michelle, Whitehead, Amy, Ellis, Deborah, Sarwar, Naveed, Enting, Deborah, Birtle, Alison, Johnson, Bernadette, Huddart, Robert, Griffiths, Gareth
Julkaisussa Clin Cancer Res (2021)

Body Mass Index in Patients Treated with Cabozantinib for Advanced Renal Cell Carcinoma: A New Prognostic Factor?

Tekijä Santoni, Matteo, Massari, Francesco, Bracarda, Sergio, Procopio, Giuseppe, Milella, Michele, De Giorgi, Ugo, Basso, Umberto, Aurilio, Gaetano, Incorvaia, Lorena, Martignetti, Angelo, Rizzo, Mimma, Cartenì, Giacomo, Grande, Enrique, Matrana, Marc R., Crabb, Simon J., Vau, Nuno, Sorgentoni, Giulia, Cimadamore, Alessia, Montironi, Rodolfo, Battelli, Nicola
Julkaisussa Diagnostics (Basel) (2021)

Venous Thromboembolism Risk in Patients With Locoregional Urothelial Tract Tumors

Tekijä Ramos, Jorge D., Wingate, Jonathan T., Gulati, Roman, Plimack, Elizabeth R., Harshman, Lauren C., Powles, Thomas, Crabb, Simon J., Niegisch, Guenter, Bellmunt, Joaquim, Ladoire, Sylvain, De Giorgi, Ugo, Hussain, Syed, Alva, Ajjai S., Baniel, Jack, Agarwal, Neeraj, Rosenberg, Jonathan E., Vaishampayan, Ulka N., Galsky, Matthew D., Yu, Evan Y.
Julkaisussa Clin Genitourin Cancer (2017)

Tumor Downstaging as an Intermediate Endpoint to Assess the Activity of Neoadjuvant Systemic Therapy in Patients With Muscle-Invasive Bladder Cancer

Tekijä Martini, Alberto, Jia, Rachel, Ferket, Bart S., Waingankar, Nikhil, Plimack, Elizabeth R., Crabb, Simon J., Harshman, Lauren C., Yu, Evan Y., Powles, Thomas, Rosenberg, Jonathan E., Pal, Sumanta K., Vaishampayan, Ulka N., Necchi, Andrea, Wiklund, N. Peter, Mehrazin, Reza, Mazumdar, Madhu, Sfakianos, John P., Galsky, Matthew D.
Julkaisussa Cancer (2019)

Venous thromboembolism in metastatic urothelial carcinoma or variant histologies: incidence, associative factors, and effect on survival

Tekijä Ramos, Jorge D., Casey, Martin F., Crabb, Simon J., Bamias, Aristotelis, Harshman, Lauren C., Wong, Yu‐Ning, Bellmunt, Joaquim, De Giorgi, Ugo, Ladoire, Sylvain, Powles, Thomas, Pal, Sumanta K., Niegisch, Guenter, Recine, Federica, Alva, Ajjai, Agarwal, Neeraj, Necchi, Andrea, Vaishampayan, Ulka N., Rosenberg, Jonathan E., Galsky, Matthew D., Yu, Evan Y.
Julkaisussa Cancer Med (2016)

COAST (Cisplatin ototoxicity attenuated by aspirin trial): A phase II double-blind, randomised controlled trial to establish if aspirin reduces cisplatin induced hearing-loss

Tekijä Crabb, Simon J., Martin, Karen, Abab, Julia, Ratcliffe, Ian, Thornton, Roger, Lineton, Ben, Ellis, Mary, Moody, Ronald, Stanton, Louise, Galanopoulou, Angeliki, Maishman, Tom, Geldart, Thomas, Bayne, Mike, Davies, Joe, Lamb, Carolynn, Popat, Sanjay, Joffe, Johnathan K., Nutting, Chris, Chester, John, Hartley, Andrew, Thomas, Gareth, Ottensmeier, Christian, Huddart, Robert, King, Emma
Julkaisussa Eur J Cancer (2017)

Neoadjuvant vs. Adjuvant Chemotherapy in Muscle Invasive Bladder Cancer (MIBC): Analysis From the RISC Database

Tekijä Del Bene, Gabriella, Calabrò, Fabio, Giannarelli, Diana, Plimack, Elizabeth R., Harshman, Lauren C., Yu, Evan Y., Crabb, Simon J., Pal, Sumanta Kumar, Alva, Ajjai S., Powles, Thomas, De Giorgi, Ugo, Agarwal, Neeraj, Bamias, Aristotelis, Ladoire, Sylvain, Necchi, Andrea, Vaishampayan, Ulka N., Niegisch, Günter, Bellmunt, Joaquim, Baniel, Jack, Galsky, Matthew D., Sternberg, Cora N.
Julkaisussa Front Oncol (2018)

Pan-AKT Inhibitor Capivasertib With Docetaxel and Prednisolone in Metastatic Castration-Resistant Prostate Cancer: A Randomized, Placebo-Controlled Phase II Trial (ProCAID)

Tekijä Crabb, Simon J., Griffiths, Gareth, Marwood, Ellice, Dunkley, Denise, Downs, Nichola, Martin, Karen, Light, Michelle, Northey, Josh, Wilding, Sam, Whitehead, Amy, Shaw, Emily, Birtle, Alison J., Bahl, Amit, Elliott, Tony, Westbury, Charlotte, Sundar, Santhanam, Robinson, Angus, Jagdev, Satinder, Kumar, Satish, Rooney, Claire, Salinas-Souza, Carolina, Stephens, Christine, Khoo, Vincent, Jones, Robert J.
Julkaisussa J Clin Oncol (2021)

Long non-coding RNAs identify a subset of luminal muscle-invasive bladder cancer patients with favorable prognosis

Tekijä de Jong, Joep J., Liu, Yang, Robertson, A. Gordon, Seiler, Roland, Groeneveld, Clarice S., van der Heijden, Michiel S., Wright, Jonathan L., Douglas, James, Dall’Era, Marc, Crabb, Simon J., van Rhijn, Bas W. G., van Kessel, Kim E. M., Davicioni, Elai, Castro, Mauro A. A., Lotan, Yair, Zwarthoff, Ellen C., Black, Peter C., Boormans, Joost L., Gibb, Ewan A.
Julkaisussa Genome Med (2019)

Real-World Data on Cabozantinib in Previously Treated Patients with Metastatic Renal Cell Carcinoma: Focus on Sequences and Prognostic Factors

Tekijä Santoni, Matteo, Heng, Daniel Y., Bracarda, Sergio, Procopio, Giuseppe, Milella, Michele, Porta, Camillo, Matrana, Marc R., Cartenì, Giacomo, Crabb, Simon J., De Giorgi, Ugo, Basso, Umberto, Masini, Cristina, Calabrò, Fabio, Vitale, Maria Giuseppa, Santini, Daniele, Massari, Francesco, Galli, Luca, Fornarini, Giuseppe, Ricotta, Riccardo, Buti, Sebastiano, Zucali, Paolo, Caffo, Orazio, Morelli, Franco, Carrozza, Francesco, Martignetti, Angelo, Gelibter, Alain, Iacovelli, Roberto, Mosca, Alessandra, Atzori, Francesco, Vau, Nuno, Incorvaia, Lorena, Ortega, Cinzia, Scarpelli, Marina, Lopez-Beltran, Antonio, Cheng, Liang, Paolucci, Vittorio, Graham, Jeffrey, Pierce, Erin, Scagliarini, Sarah, Sepe, Pierangela, Verzoni, Elena, Merler, Sara, Rizzo, Mimma, Sorgentoni, Giulia, Conti, Alessandro, Piva, Francesco, Cimadamore, Alessia, Montironi, Rodolfo, Battelli, Nicola
Julkaisussa Cancers (Basel) (2019)