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Dichotomous roles of claudins as tumor promoters or suppressors: lessons from knockout mice

Claudins are a family of integral tight junction proteins that regulate paracellular permeability in polarized epithelia. Overexpression or reduction of claudins can both promote and limit cancer progression, revealing complex dichotomous roles for claudins depending on cellular context. In contrast...

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Bibliografski detalji
Izdano u:Cell Mol Life Sci
Glavni autori: Kage, Hidenori, Flodby, Per, Zhou, Beiyun, Borok, Zea
Format: Artigo
Jezik:Inglês
Izdano: Springer International Publishing 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6858953/
https://ncbi.nlm.nih.gov/pubmed/31332482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-019-03238-7
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