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RBPJ-dependent Notch signaling initiates the T cell program in a subset of thymus-seeding progenitors
T cell specification and commitment requires Notch signaling. Although the requirement for Notch signaling during intrathymic T cell development is known, it is still unclear whether the onset of T cell priming can occur in a pre-thymic niche and whether RBPJ-dependent Notch signaling has a role dur...
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| Pubblicato in: | Nat Immunol |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6858571/ https://ncbi.nlm.nih.gov/pubmed/31636466 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41590-019-0518-7 |
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