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Profiling the mouse brain endothelial transcriptome in health and disease models reveals a core blood-brain barrier dysfunction module

Blood vessels in the central nervous system (CNS) form a specialized and critical structure, the blood-brain barrier (BBB). We present a resource to understand the molecular mechanisms that regulate BBB function in health and dysfunction during disease. Using endothelial cell enrichment and RNA sequ...

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Detalhes bibliográficos
Publicado no:Nat Neurosci
Main Authors: Munji, Roeben Nocon, Soung, Allison Luen, Weiner, Geoffrey Aaron, Sohet, Fabien, Semple, Bridgette Deanne, Trivedi, Alpa, Gimlin, Kayleen, Kotoda, Masakazu, Korai, Masaaki, Aydin, Sidar, Batugal, Austin, Cabangcala, Anne Christelle, Schupp, Patrick Georg, Oldham, Michael Clark, Hashimoto, Tomoki, Noble-Haeusslein, Linda J., Daneman, Richard
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6858546/
https://ncbi.nlm.nih.gov/pubmed/31611708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41593-019-0497-x
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