CRISPR/Cas9-mediated editing of Δ5 and Δ6 desaturases impairs Δ8-desaturation and docosahexaenoic acid synthesis in Atlantic salmon (Salmo salar L.)

The in vivo functions of Atlantic salmon fatty acyl desaturases (fads2), Δ6fads2-a, Δ6fads2-b, Δ6fads2-c and Δ5fads2 in long chain polyunsaturated fatty acid (LC-PUFA) synthesis in salmon and fish in general remains to be elucidated. Here, we investigate in vivo functions and in vivo functional redu...

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Vydáno v:Sci Rep
Hlavní autoři: Datsomor, Alex K., Olsen, Rolf E., Zic, Nikola, Madaro, Angelico, Bones, Atle M., Edvardsen, Rolf B., Wargelius, Anna, Winge, Per
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6858459/
https://ncbi.nlm.nih.gov/pubmed/31729437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-53316-w
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