Targeted Mutagenesis in Atlantic Salmon (Salmo salar L.) Using the CRISPR/Cas9 System Induces Complete Knockout Individuals in the F0 Generation

por Edvardsen, Rolf B., Leininger, Sven, Kleppe, Lene, Skaftnesmo, Kai Ove, Wargelius, Anna
Publicado 2014

Genomic organization and gene expression of the multiple globins in Atlantic cod: conservation of globin-flanking genes in chordates infers the origin of the vertebrate globin clus...

por Wetten, Ola F, Nederbragt, Alexander J, Wilson, Robert C, Jakobsen, Kjetill S, Edvardsen, Rolf B, Andersen, Øivind
Publicado 2010

Diet affects the redox system in developing Atlantic cod (Gadus morhua) larvae

por Penglase, Samuel, Edvardsen, Rolf B., Furmanek, Tomasz, Rønnestad, Ivar, Karlsen, Ørjan, van der Meeren, Terje, Hamre, Kristin
Publicado en Redox Biol (2015)

Maternal 3’UTRs: from egg to onset of zygotic transcription in Atlantic cod

por Kleppe, Lene, Edvardsen, Rolf B, Kuhl, Heiner, Malde, Ketil, Furmanek, Tomasz, Drivenes, Øyvind, Reinhardt, Richard, Taranger, Geir L, Wargelius, Anna
Publicado 2012

Dnd knockout ablates germ cells and demonstrates germ cell independent sex differentiation in Atlantic salmon

por Wargelius, Anna, Leininger, Sven, Skaftnesmo, Kai Ove, Kleppe, Lene, Andersson, Eva, Taranger, Geir Lasse, Schulz, Rüdiger W, Edvardsen, Rolf B
Publicado en Sci Rep (2016)

Novel adverse outcome pathways revealed by chemical genetics in a developing marine fish

por Sørhus, Elin, Incardona, John P, Furmanek, Tomasz, Goetz, Giles W, Scholz, Nathaniel L, Meier, Sonnich, Edvardsen, Rolf B, Jentoft, Sissel
Publicado en eLife (2017)

CRISPR/Cas9-mediated editing of Δ5 and Δ6 desaturases impairs Δ8-desaturation and docosahexaenoic acid synthesis in Atlantic salmon (Salmo salar L.)

por Datsomor, Alex K., Olsen, Rolf E., Zic, Nikola, Madaro, Angelico, Bones, Atle M., Edvardsen, Rolf B., Wargelius, Anna, Winge, Per
Publicado en Sci Rep (2019)

Unexpected Interaction with Dispersed Crude Oil Droplets Drives Severe Toxicity in Atlantic Haddock Embryos

por Sørhus, Elin, Edvardsen, Rolf B., Karlsen, Ørjan, Nordtug, Trond, van der Meeren, Terje, Thorsen, Anders, Harman, Christopher, Jentoft, Sissel, Meier, Sonnich
Publicado en PLoS One (2015)

Rescue of germ cells in dnd crispant embryos opens the possibility to produce inherited sterility in Atlantic salmon

por Güralp, Hilal, Skaftnesmo, Kai O., Kjærner-Semb, Erik, Straume, Anne Hege, Kleppe, Lene, Schulz, Rüdiger W., Edvardsen, Rolf B., Wargelius, Anna
Publicado en Sci Rep (2020)

Author Correction: Rescue of germ cells in dnd crispant embryos opens the possibility to produce inherited sterility in Atlantic salmon

por Güralp, Hilal, Skaftnesmo, Kai O., Kjærner‑Semb, Erik, Straume, Anne Hege, Kleppe, Lene, Schulz, Rüdiger W., Edvardsen, Rolf B., Wargelius, Anna
Publicado en Sci Rep (2021)

Sex steroid production associated with puberty is absent in germ cell-free salmon

por Kleppe, Lene, Andersson, Eva, Skaftnesmo, Kai Ove, Edvardsen, Rolf B., Fjelldal, Per Gunnar, Norberg, Birgitta, Bogerd, Jan, Schulz, Rüdiger W., Wargelius, Anna
Publicado en Sci Rep (2017)

Targeted mutagenesis of ∆5 and ∆6 fatty acyl desaturases induce dysregulation of lipid metabolism in Atlantic salmon (Salmo salar)

por Jin, Yang, Datsomor, Alex K., Olsen, Rolf E., Vik, Jon Olav, Torgersen, Jacob S., Edvardsen, Rolf B., Wargelius, Anna, Winge, Per, Grammes, Fabian
Publicado en BMC Genomics (2020)

Genomic architecture of haddock (Melanogrammus aeglefinus) shows expansions of innate immune genes and short tandem repeats

por Tørresen, Ole K., Brieuc, Marine S. O., Solbakken, Monica H., Sørhus, Elin, Nederbragt, Alexander J., Jakobsen, Kjetill S., Meier, Sonnich, Edvardsen, Rolf B., Jentoft, Sissel
Publicado en BMC Genomics (2018)

Human-induced evolution caught in action: SNP-array reveals rapid amphi-atlantic spread of pesticide resistance in the salmon ecotoparasite Lepeophtheirus salmonis

por Besnier, Francois, Kent, Matthew, Skern-Mauritzen, Rasmus, Lien, Sigbjørn, Malde, Ketil, Edvardsen, Rolf B, Taylor, Simon, Ljungfeldt, Lina ER, Nilsen, Frank, Glover, Kevin A
Publicado en BMC Genomics (2014)

CRISPR/Cas9-mediated ablation of elovl2 in Atlantic salmon (Salmo salar L.) inhibits elongation of polyunsaturated fatty acids and induces Srebp-1 and target genes

por Datsomor, Alex K., Zic, Nikola, Li, Keshuai, Olsen, Rolf E., Jin, Yang, Vik, Jon Olav, Edvardsen, Rolf B., Grammes, Fabian, Wargelius, Anna, Winge, Per
Publicado en Sci Rep (2019)

The influence of vgll3 genotypes on sea age at maturity is altered in farmed mowi strain Atlantic salmon

por Ayllon, Fernando, Solberg, Monica F., Glover, Kevin A., Mohammadi, Faezeh, Kjærner-Semb, Erik, Fjelldal, Per Gunnar, Andersson, Eva, Hansen, Tom, Edvardsen, Rolf B., Wargelius, Anna
Publicado en BMC Genet (2019)

Loss of stra8 Increases Germ Cell Apoptosis but Is Still Compatible With Sperm Production in Atlantic Salmon (Salmo salar)

por Skaftnesmo, Kai O., Crespo, Diego, Kleppe, Lene, Andersson, Eva, Edvardsen, Rolf B., Norberg, Birgitta, Fjelldal, Per Gunnar, Hansen, Tom J., Schulz, Rüdiger W., Wargelius, Anna
Publicado en Front Cell Dev Biol (2021)

The initiation of puberty in Atlantic salmon brings about large changes in testicular gene expression that are modulated by the energy status

por Crespo, Diego, Bogerd, Jan, Sambroni, Elisabeth, LeGac, Florence, Andersson, Eva, Edvardsen, Rolf B., Bergman, Elisabeth Jönsson, Björnsson, Björn Thrandur, Taranger, Geir Lasse, Schulz, Rüdiger W.
Publicado en BMC Genomics (2019)

Crude oil exposures reveal roles for intracellular calcium cycling in haddock craniofacial and cardiac development

por Sørhus, Elin, Incardona, John P., Karlsen, Ørjan, Linbo, Tiffany, Sørensen, Lisbet, Nordtug, Trond, van der Meeren, Terje, Thorsen, Anders, Thorbjørnsen, Maja, Jentoft, Sissel, Edvardsen, Rolf B., Meier, Sonnich
Publicado en Sci Rep (2016)

Atlantic salmon populations reveal adaptive divergence of immune related genes - a duplicated genome under selection

por Kjærner-Semb, Erik, Ayllon, Fernando, Furmanek, Tomasz, Wennevik, Vidar, Dahle, Geir, Niemelä, Eero, Ozerov, Mikhail, Vähä, Juha-Pekka, Glover, Kevin A., Rubin, Carl J., Wargelius, Anna, Edvardsen, Rolf B.
Publicado en BMC Genomics (2016)