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Exploring the limitations of biophysical propensity scales coupled with machine learning for protein sequence analysis

Machine learning (ML) is ubiquitous in bioinformatics, due to its versatility. One of the most crucial aspects to consider while training a ML model is to carefully select the optimal feature encoding for the problem at hand. Biophysical propensity scales are widely adopted in structural bioinformat...

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Publicat a:Sci Rep
Autors principals: Raimondi, Daniele, Orlando, Gabriele, Vranken, Wim F., Moreau, Yves
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2019
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6858301/
https://ncbi.nlm.nih.gov/pubmed/31729443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-53324-w
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