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Large-scale in-silico statistical mutagenesis analysis sheds light on the deleteriousness landscape of the human proteome
Next generation sequencing technologies are providing increasing amounts of sequencing data, paving the way for improvements in clinical genetics and precision medicine. The interpretation of the observed genomic variants in the light of their phenotypic effects is thus emerging as a crucial task to...
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| Pubblicato in: | Sci Rep |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group UK
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6242909/ https://ncbi.nlm.nih.gov/pubmed/30451933 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-34959-7 |
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