The CoDiNOS trial protocol: an international randomised controlled trial of intravenous sildenafil versus inhaled nitric oxide for the treatment of pulmonary hypertension in neonates with congenital diaphragmatic hernia

INTRODUCTION: Congenital diaphragmatic hernia (CDH) is a developmental defect of the diaphragm that impairs normal lung development, causing pulmonary hypertension (PH). PH in CDH newborns is the main determinant for morbidity and mortality. Different therapies are still mainly based on ‘trial and e...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:BMJ Open
Prif Awduron: Cochius-den Otter, Suzan, Schaible, Thomas, Greenough, Anne, van Heijst, Arno, Patel, Neil, Allegaert, Karel, van Rosmalen, Joost, Tibboel, Dick
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BMJ Publishing Group 2019
Pynciau:
Paediatrics
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6858099/
https://ncbi.nlm.nih.gov/pubmed/31694851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjopen-2019-032122
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