The CoDiNOS trial protocol: an international randomised controlled trial of intravenous sildenafil versus inhaled nitric oxide for the treatment of pulmonary hypertension in neonates with congenital diaphragmatic hernia

INTRODUCTION: Congenital diaphragmatic hernia (CDH) is a developmental defect of the diaphragm that impairs normal lung development, causing pulmonary hypertension (PH). PH in CDH newborns is the main determinant for morbidity and mortality. Different therapies are still mainly based on ‘trial and e...

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Bibliografski detalji
Izdano u:BMJ Open
Glavni autori: Cochius-den Otter, Suzan, Schaible, Thomas, Greenough, Anne, van Heijst, Arno, Patel, Neil, Allegaert, Karel, van Rosmalen, Joost, Tibboel, Dick
Format: Artigo
Jezik:Inglês
Izdano: BMJ Publishing Group 2019
Teme:
Paediatrics
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6858099/
https://ncbi.nlm.nih.gov/pubmed/31694851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjopen-2019-032122
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