The CoDiNOS trial protocol: an international randomised controlled trial of intravenous sildenafil versus inhaled nitric oxide for the treatment of pulmonary hypertension in neonates with congenital diaphragmatic hernia

INTRODUCTION: Congenital diaphragmatic hernia (CDH) is a developmental defect of the diaphragm that impairs normal lung development, causing pulmonary hypertension (PH). PH in CDH newborns is the main determinant for morbidity and mortality. Different therapies are still mainly based on ‘trial and e...

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Detalhes bibliográficos
Publicado no:BMJ Open
Main Authors: Cochius-den Otter, Suzan, Schaible, Thomas, Greenough, Anne, van Heijst, Arno, Patel, Neil, Allegaert, Karel, van Rosmalen, Joost, Tibboel, Dick
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2019
Assuntos:
Paediatrics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6858099/
https://ncbi.nlm.nih.gov/pubmed/31694851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjopen-2019-032122
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