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Dynamic UTR Usage Regulates Alternative Translation to Modulate Gap Junction Formation during Stress and Aging

Connexin43 (Cx43; gene name GJA1) is the most ubiquitously expressed gap junction protein, and understanding of its regulation largely falls under transcription and post-translational modification. In addition to Cx43, Gja1 mRNA encodes internally translated isoforms regulating gap junction formatio...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Zeitz, Michael J., Calhoun, Patrick J., James, Carissa C., Taetzsch, Thomas, George, Kijana K., Robel, Stefanie, Valdez, Gregorio, Smyth, James W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6857847/
https://ncbi.nlm.nih.gov/pubmed/31141695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2019.04.114
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