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Alternative mechanisms of translation initiation: an emerging dynamic regulator of the proteome in health and disease.

Eukaryotic mRNAs were historically thought to rely exclusively on recognition and binding of their 5’ cap by initiation factors to effect protein translation. While internal ribosome entry sites (IRESs) are well accepted as necessary for the cap-independent translation of many viral genomes, there i...

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Detalhes bibliográficos
Publicado no:Life Sci
Main Authors: James, Carissa C., Smyth, James W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6345546/
https://ncbi.nlm.nih.gov/pubmed/30290184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.lfs.2018.09.054
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