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PTH/PTHrP Receptor Signaling, Allostery, and Structures

The parathyroid hormone (PTH) type 1 receptor (PTHR) is the canonical G protein-coupled receptor (GPCR) for PTH and PTH-related protein (PTHrP) and the key regulator of calcium homeostasis and bone turnover. PTHR function is critical for human health to maintain homeostatic control of ionized serum...

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Detalles Bibliográficos
Publicado en:Trends Endocrinol Metab
Autores principales: Sutkeviciute, Ieva, Clark, Lisa J., White, Alex D., Gardella, Thomas J., Vilardaga, Jean-Pierre
Formato: Artigo
Lenguaje:Inglês
Publicado: 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6857722/
https://ncbi.nlm.nih.gov/pubmed/31699241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tem.2019.07.011
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