IL-6 and IL-8 Are Linked With Myeloid-Derived Suppressor Cell Accumulation and Correlate With Poor Clinical Outcomes in Melanoma Patients

We sought to identify tumor-secreted factors that altered the frequency of MDSCs and correlated with clinical outcomes in advanced melanoma patients. We focused our study on several of the many factors involved in the expansion and mobilization of MDSCs. These were identified by measuring circulatin...

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Bibliografiske detaljer
Udgivet i:Front Oncol
Main Authors: Tobin, Richard P., Jordan, Kimberly R., Kapoor, Puja, Spongberg, Eric, Davis, Dana, Vorwald, Victoria M., Couts, Kasey L., Gao, Dexiang, Smith, Derek E., Borgers, Jessica S. W., Robinson, Steven, Amato, Carol, Gonzalez, Rene, Lewis, Karl D., Robinson, William A., Borges, Virginia F., McCarter, Martin D.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2019
Fag:
Oncology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6857649/
https://ncbi.nlm.nih.gov/pubmed/31781510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2019.01223
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