IL-6 and IL-8 Are Linked With Myeloid-Derived Suppressor Cell Accumulation and Correlate With Poor Clinical Outcomes in Melanoma Patients

We sought to identify tumor-secreted factors that altered the frequency of MDSCs and correlated with clinical outcomes in advanced melanoma patients. We focused our study on several of the many factors involved in the expansion and mobilization of MDSCs. These were identified by measuring circulatin...

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Bibliografske podrobnosti
izdano v:Front Oncol
Main Authors: Tobin, Richard P., Jordan, Kimberly R., Kapoor, Puja, Spongberg, Eric, Davis, Dana, Vorwald, Victoria M., Couts, Kasey L., Gao, Dexiang, Smith, Derek E., Borgers, Jessica S. W., Robinson, Steven, Amato, Carol, Gonzalez, Rene, Lewis, Karl D., Robinson, William A., Borges, Virginia F., McCarter, Martin D.
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2019
Teme:
Oncology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6857649/
https://ncbi.nlm.nih.gov/pubmed/31781510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2019.01223
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