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Ras and exosome signaling

Ras gene (HRAS, NRAS, and KRAS) has been observed to be mutated and hyper-activated in a significant proportion of cancers. However, mutant Ras remains a challenging therapeutic target. Similarly, inhibition of targets upstream and downstream of Ras has shown limited clinical utility. There have bee...

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Bibliografische gegevens
Gepubliceerd in:Semin Cancer Biol
Hoofdauteurs: Sexton, Rachel E., Mpilla, Gabriel, Kim, Steve, Philip, Philip A., Azmi, Asfar S.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2019
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6857536/
https://ncbi.nlm.nih.gov/pubmed/30769101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcancer.2019.02.004
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