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Ras and exosome signaling
Ras gene (HRAS, NRAS, and KRAS) has been observed to be mutated and hyper-activated in a significant proportion of cancers. However, mutant Ras remains a challenging therapeutic target. Similarly, inhibition of targets upstream and downstream of Ras has shown limited clinical utility. There have bee...
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| Publicado no: | Semin Cancer Biol |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6857536/ https://ncbi.nlm.nih.gov/pubmed/30769101 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcancer.2019.02.004 |
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