Copenhagen Head Injury Ciclosporin Study: A Phase IIa Safety, Pharmacokinetics, and Biomarker Study of Ciclosporin in Severe Traumatic Brain Injury Patients

Traumatic brain injury (TBI) contributes to almost one third of all trauma-related deaths, and those that survive often suffer from long-term physical and cognitive deficits. Ciclosporin (cyclosporine, cyclosporin A) has shown promising neuroprotective properties in pre-clinical TBI models. The Cope...

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Détails bibliographiques
Publié dans:J Neurotrauma
Auteurs principaux: Kelsen, Jesper, Karlsson, Michael, Hansson, Magnus J., Yang, Zhihui, Fischer, Walter, Hugerth, Matilda, Nordström, Carl-Henrik, Åstrand, Ramona, Keep, Marcus F., Kilbaugh, Todd, Wang, Kevin K.W., Møller, Kirsten, Juhler, Marianne, Elmér, Eskil
Format: Artigo
Langue:Inglês
Publié: Mary Ann Liebert, Inc., publishers 2019
Sujets:
Original Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6857463/
https://ncbi.nlm.nih.gov/pubmed/31210099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/neu.2018.6369
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