Neuroprotective Effects of Cyclosporine in a Porcine Pre-Clinical Trial of Focal Traumatic Brain Injury

Mitochondrial dysfunction is thought to be a hallmark of traumatic brain injury (TBI) and plays a pivotal role in the resulting cellular injury. Cyclophilin D–mediated activation of the mitochondrial permeability transition pore has been suggested to contribute to this secondary injury cascade. Cycl...

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Detalhes bibliográficos
Publicado no:J Neurotrauma
Main Authors: Karlsson, Michael, Pukenas, Bryan, Chawla, Sanjeev, Ehinger, Johannes K., Plyler, Ross, Stolow, Madeline, Gabello, Melissa, Hugerth, Matilda, Elmér, Eskil, Hansson, Magnus J., Margulies, Susan, Kilbaugh, Todd
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc., publishers 2019
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6306685/
https://ncbi.nlm.nih.gov/pubmed/29929438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/neu.2018.5706
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