Janus kinase inhibitors for the treatment of rheumatoid arthritis demonstrate similar profiles of in vitro cytokine receptor inhibition

Janus kinase (JAK) inhibitors have emerged as an effective class of therapies for various inflammatory diseases such as rheumatoid arthritis (RA). JAK inhibitors function intracellularly by modulating the catalytic activity of JAKs and disrupting the receptor‐mediated signaling of multiple cytokines...

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Detalhes bibliográficos
Publicado no:Pharmacol Res Perspect
Main Authors: Dowty, Martin E., Lin, Tsung H., Jesson, Michael I., Hegen, Martin, Martin, David A., Katkade, Vaibhav, Menon, Sujatha, Telliez, Jean‐Baptiste
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6857076/
https://ncbi.nlm.nih.gov/pubmed/31832202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prp2.537
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