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Deep mutational scanning of the Neisseria meningitidis major pilin reveals the importance of pilus tip‐mediated adhesion
Type IV pili (TFP) are multifunctional micrometer‐long filaments expressed at the surface of many prokaryotes. In Neisseria meningitidis, TFP are crucial for virulence. Indeed, these homopolymers of the major pilin PilE mediate interbacterial aggregation and adhesion to host cells. However, the mech...
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| 發表在: | EMBO J |
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| Main Authors: | , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
John Wiley and Sons Inc.
2019
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6856618/ https://ncbi.nlm.nih.gov/pubmed/31609039 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2019102145 |
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