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Deep mutational scanning of the Neisseria meningitidis major pilin reveals the importance of pilus tip‐mediated adhesion

Type IV pili (TFP) are multifunctional micrometer‐long filaments expressed at the surface of many prokaryotes. In Neisseria meningitidis, TFP are crucial for virulence. Indeed, these homopolymers of the major pilin PilE mediate interbacterial aggregation and adhesion to host cells. However, the mech...

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Detaylı Bibliyografya
Yayımlandı:EMBO J
Asıl Yazarlar: Kennouche, Paul, Charles‐Orszag, Arthur, Nishiguchi, Daiki, Goussard, Sylvie, Imhaus, Anne‐Flore, Dupré, Mathieu, Chamot‐Rooke, Julia, Duménil, Guillaume
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2019
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6856618/
https://ncbi.nlm.nih.gov/pubmed/31609039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2019102145
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