Inhibitors of the Neisseria meningitidis PilF ATPase provoke type IV pilus disassembly

Despite the availability of antibiotics and vaccines, Neisseria meningitidis remains a major cause of meningitis and sepsis in humans. Due to its extracellular lifestyle, bacterial adhesion to host cells constitutes an attractive therapeutic target. Here, we present a high-throughput microscopy-base...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Aubey, Flore, Corre, Jean-Philippe, Kong, Youxin, Xu, Ximing, Obino, Dorian, Goussard, Sylvie, Lapeyrere, Catherine, Souphron, Judith, Couturier, Cedric, Renard, Stéphane, Duménil, Guillaume
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2019
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6486710/
https://ncbi.nlm.nih.gov/pubmed/30948644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1817757116
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