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A human-on-a-chip approach to tackling rare diseases

Drug development for rare diseases, classified as diseases with a prevalence of <200 000 patients, is limited by high cost of research and low target population. Owing to a lack of representative disease models, research has been challenging for orphan drugs. Human-on-a-chip (HoaC) technology, wh...

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Bibliographic Details
Published in:Drug Discov Today
Main Authors: de Mello, Camilly P. Pires, Rumsey, John, Slaughter, Victoria, Hickman, James J.
Format: Artigo
Language:Inglês
Published: 2019
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6856435/
https://ncbi.nlm.nih.gov/pubmed/31412288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drudis.2019.08.001
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