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Heterologous Expression of a Cryptic Gene Cluster from Streptomyces leeuwenhoekii C34(T) Yields a Novel Lasso Peptide, Leepeptin

Analysis of the genome sequence of Streptomyces leeuwenhoekii C34(T) identified biosynthetic gene clusters (BGCs) for three different lasso peptides (Lp1, Lp2, and Lp3) which were not known to be made by the strain. Lasso peptides represent relatively new members of the RiPP (ribosomally synthesized...

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Detalhes bibliográficos
Publicado no:Appl Environ Microbiol
Main Authors: Gomez-Escribano, Juan Pablo, Castro, Jean Franco, Razmilic, Valeria, Jarmusch, Scott A., Saalbach, Gerhard, Ebel, Rainer, Jaspars, Marcel, Andrews, Barbara, Asenjo, Juan A., Bibb, Mervyn J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6856326/
https://ncbi.nlm.nih.gov/pubmed/31562169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.01752-19
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