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Engineering Streptomyces coelicolor for heterologous expression of secondary metabolite gene clusters

We have constructed derivatives of Streptomyces coelicolor M145 as hosts for the heterologous expression of secondary metabolite gene clusters. To remove potentially competitive sinks of carbon and nitrogen, and to provide a host devoid of antibiotic activity, we deleted four endogenous secondary me...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Gomez‐Escribano, Juan Pablo, Bibb, Mervyn J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Blackwell Publishing Ltd 2011
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3818861/
https://ncbi.nlm.nih.gov/pubmed/21342466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1751-7915.2010.00219.x
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