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Metabolic programming determines the lineage-differentiation fate of murine bone marrow stromal progenitor cells
Enhanced bone marrow adipogenesis and impaired osteoblastogenesis have been observed in obesity, suggesting that the metabolic microenvironment regulates bone marrow adipocyte and osteoblast progenitor differentiation fate. To determine the molecular mechanisms, we studied two immortalized murine ce...
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| 發表在: | Bone Res |
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| Main Authors: | , , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Nature Publishing Group UK
2019
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6856123/ https://ncbi.nlm.nih.gov/pubmed/31754546 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41413-019-0076-5 |
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