Metabolic programming determines the lineage-differentiation fate of murine bone marrow stromal progenitor cells

Enhanced bone marrow adipogenesis and impaired osteoblastogenesis have been observed in obesity, suggesting that the metabolic microenvironment regulates bone marrow adipocyte and osteoblast progenitor differentiation fate. To determine the molecular mechanisms, we studied two immortalized murine ce...

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Detalhes bibliográficos
Publicado no:Bone Res
Main Authors: Tencerova, Michaela, Rendina-Ruedy, Elizabeth, Neess, Ditte, Færgeman, Nils, Figeac, Florence, Ali, Dalia, Danielsen, Morten, Haakonsson, Anders, Rosen, Clifford J., Kassem, Moustapha
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6856123/
https://ncbi.nlm.nih.gov/pubmed/31754546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41413-019-0076-5
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