Metabolic programming determines the lineage-differentiation fate of murine bone marrow stromal progenitor cells

Enhanced bone marrow adipogenesis and impaired osteoblastogenesis have been observed in obesity, suggesting that the metabolic microenvironment regulates bone marrow adipocyte and osteoblast progenitor differentiation fate. To determine the molecular mechanisms, we studied two immortalized murine ce...

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Bibliographic Details
Published in:Bone Res
Main Authors: Tencerova, Michaela, Rendina-Ruedy, Elizabeth, Neess, Ditte, Færgeman, Nils, Figeac, Florence, Ali, Dalia, Danielsen, Morten, Haakonsson, Anders, Rosen, Clifford J., Kassem, Moustapha
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6856123/
https://ncbi.nlm.nih.gov/pubmed/31754546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41413-019-0076-5
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