Optimal Sampling Strategies for Therapeutic Drug Monitoring of First-Line Tuberculosis Drugs in Patients with Tuberculosis

BACKGROUND: The 24-h area under the concentration–time curve (AUC(24))/minimal inhibitory concentration ratio is the best predictive pharmacokinetic/pharmacodynamic (PK/PD) parameter of the efficacy of first-line anti-tuberculosis (TB) drugs. An optimal sampling strategy (OSS) is useful for accurate...

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Publicado en:Clin Pharmacokinet
Autores principales: Saktiawati, Antonia Morita I., Harkema, Marcel, Setyawan, Althaf, Subronto, Yanri W., Sumardi, Stienstra, Ymkje, Aarnoutse, Rob E., Magis-Escurra, Cecile, Kosterink, Jos G. W., van der Werf, Tjip S., Alffenaar, Jan-Willem C., Sturkenboom, Marieke G. G.
Formato: Artigo
Lenguaje:Inglês
Publicado: Springer International Publishing 2019
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Original Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6856034/
https://ncbi.nlm.nih.gov/pubmed/30997650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40262-019-00763-3
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