Tumor Necrosis Factor-α-Mediated Metaplastic Inhibition of LTP Is Constitutively Engaged in an Alzheimer's Disease Model

LTP, a fundamental mechanism of learning and memory, is a highly regulated process. One form of regulation is metaplasticity (i.e., the activity-dependent and long-lasting changes in neuronal state that orchestrate the direction, magnitude, and persistence of future synaptic plasticity). We have pre...

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Bibliographic Details
Published in:J Neurosci
Main Authors: Singh, Anurag, Jones, Owen D., Mockett, Bruce G., Ohline, Shane M., Abraham, Wickliffe C.
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 2019
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Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6855674/
https://ncbi.nlm.nih.gov/pubmed/31570539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1492-19.2019
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