A Voltage-Based STDP Rule Combined with Fast BCM-Like Metaplasticity Accounts for LTP and Concurrent “Heterosynaptic” LTD in the Dentate Gyrus In Vivo

Long-term potentiation (LTP) and long-term depression (LTD) are widely accepted to be synaptic mechanisms involved in learning and memory. It remains uncertain, however, which particular activity rules are utilized by hippocampal neurons to induce LTP and LTD in behaving animals. Recent experiments...

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Bibliografiske detaljer
Udgivet i:PLoS Comput Biol
Main Authors: Jedlicka, Peter, Benuskova, Lubica, Abraham, Wickliffe C.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4636250/
https://ncbi.nlm.nih.gov/pubmed/26544038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1004588
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