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A Voltage-Based STDP Rule Combined with Fast BCM-Like Metaplasticity Accounts for LTP and Concurrent “Heterosynaptic” LTD in the Dentate Gyrus In Vivo

Long-term potentiation (LTP) and long-term depression (LTD) are widely accepted to be synaptic mechanisms involved in learning and memory. It remains uncertain, however, which particular activity rules are utilized by hippocampal neurons to induce LTP and LTD in behaving animals. Recent experiments...

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Detalhes bibliográficos
Publicado no:PLoS Comput Biol
Main Authors: Jedlicka, Peter, Benuskova, Lubica, Abraham, Wickliffe C.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4636250/
https://ncbi.nlm.nih.gov/pubmed/26544038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1004588
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