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Controlled Detonation: Evolution of Necroptosis in Pathogen Defense

Necroptosis is a lytic form of programmed cell death that involves the swelling and rupture of dying cells. While several necroptosis-inducing stimuli have been defined, in most cells this pathway is kept in check by the action of the pro-apoptotic protease caspase-8 and the IAP ubiquitin ligases. H...

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Detalhes bibliográficos
Publicado no:Immunol Cell Biol
Main Authors: Brault, Michelle, Oberst, Andrew
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6855669/
https://ncbi.nlm.nih.gov/pubmed/27909314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/icb.2016.117
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