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Polycystin 2 regulates mitochondrial calcium signaling, bioenergetics, and dynamics through mitofusin 2

Mitochondria and the endoplasmic reticulum (ER) have an intimate functional relationship due to tethering proteins that bring their membranes in close (~30 nm) apposition. One function of this inter-organellar junction is to increase the efficiency of Ca(2+) transfer into mitochondria, thus stimulat...

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Detalhes bibliográficos
Publicado no:Sci Signal
Main Authors: Kuo, Ivana Y., Brill, Allison L., Lemos, Fernanda O., Jiang, Jason Y., Falcone, Jeffrey L., Kimmerling, Erica P., Cai, Yiqiang, Dong, Ke, Kaplan, David L., Wallace, Darren P., Hofer, Aldebaran M., Ehrlich, Barbara E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6855602/
https://ncbi.nlm.nih.gov/pubmed/31064883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aat7397
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