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Chromatin dynamics and the transcriptional competence of HSV-1 genomes during lytic infections

During latent infections with herpes simplex virus 1 (HSV-1), viral transcription is restricted and the genomes are mostly maintained in silenced chromatin, whereas in lytically infected cells all viral genes are transcribed and the genomes are dynamically chromatinized. Histones in the viral chroma...

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Bibliographische Detailangaben
Veröffentlicht in:PLoS Pathog
Hauptverfasser: Hu, MiYao, Depledge, Daniel P., Flores Cortes, Esteban, Breuer, Judith, Schang, Luis M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2019
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6855408/
https://ncbi.nlm.nih.gov/pubmed/31725813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008076
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