Role of PI3K/Akt and MEK/ERK Signalling in cAMP/Epac-Mediated Endothelial Barrier Stabilisation

BACKGROUND AND AIMS: Activation of the cAMP/Epac signalling stabilises endothelial barrier function. Moreover, its activation is accompanied by an activation of PI3K/Akt and MEK/ERK signalling in diverse cell types but their impact on endothelial barrier function is largely unknown. Here the role of...

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Udgivet i:Front Physiol
Main Authors: Gündüz, Dursun, Troidl, Christian, Tanislav, Christian, Rohrbach, Susanne, Hamm, Christian, Aslam, Muhammad
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2019
Fag:
Physiology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6855264/
https://ncbi.nlm.nih.gov/pubmed/31787905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2019.01387
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