Novel DNA methylation biomarkers show high sensitivity and specificity for blood-based detection of colorectal cancer—a clinical biomarker discovery and validation study

BACKGROUND: Early detection plays an essential role to reduce colorectal cancer (CRC) mortality. While current screening methods suffer from poor compliance, liquid biopsy-based strategies for cancer detection is rapidly gaining promise. Here, we describe the development of TriMeth, a minimal-invasi...

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Vydáno v:Clin Epigenetics
Hlavní autoři: Jensen, Sarah Østrup, Øgaard, Nadia, Ørntoft, Mai-Britt Worm, Rasmussen, Mads Heilskov, Bramsen, Jesper Bertram, Kristensen, Helle, Mouritzen, Peter, Madsen, Mogens Rørbæk, Madsen, Anders Husted, Sunesen, Kåre Gotschalck, Iversen, Lene Hjerrild, Laurberg, Søren, Christensen, Ib Jarle, Nielsen, Hans Jørgen, Andersen, Claus Lindbjerg
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2019
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6854894/
https://ncbi.nlm.nih.gov/pubmed/31727158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-019-0757-3
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