Myeloid-derived suppressor cell function and epigenetic expression evolves over time after surgical sepsis

BACKGROUND: Sepsis is an increasingly significant challenge throughout the world as one of the major causes of patient morbidity and mortality. Central to the host immunologic response to sepsis is the increase in circulating myeloid-derived suppressor cells (MDSCs), which have been demonstrated to...

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Detalhes bibliográficos
Publicado no:Crit Care
Main Authors: Hollen, McKenzie K., Stortz, Julie A., Darden, Dijoia, Dirain, Marvin L., Nacionales, Dina C., Hawkins, Russell B., Cox, Michael C., Lopez, Maria-Cecilia, Rincon, Jaimar C., Ungaro, Ricardo, Wang, Zhongkai, Wu, Quran, Brumback, Babette, Gauthier, Marie-Pierre L., Kladde, Michael, Leeuwenburgh, Christiaan, Segal, Mark, Bihorac, Azra, Brakenridge, Scott, Moore, Frederick A., Baker, Henry V., Mohr, Alicia M., Moldawer, Lyle L., Efron, Philip A.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
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Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6854728/
https://ncbi.nlm.nih.gov/pubmed/31722736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13054-019-2628-x
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