mTOR pathway in human cardiac hypertrophy caused by LEOPARD syndrome: a different role compared with animal models?

BACKGROUND: Animal studies suggested that blocking the activation of the mammalian target of rapamycin (mTOR) pathway might be effective to treat cardiac hypertrophy in LEOPARD syndrome (LS) caused by PTPN11 mutations. RESULTS: In the present study, mTOR pathway activity was examined in human myocar...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Orphanet J Rare Dis
Autors principals: Cui, Hao, Song, Lei, Zhu, Changsheng, Zhang, Ce, Tang, Bing, Wang, Shengwei, Wu, Guixin, Zou, Yubao, Huang, Xiaohong, Hui, Rutai, Wang, Shuiyun, Wang, Jizheng
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2019
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6854668/
https://ncbi.nlm.nih.gov/pubmed/31722741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13023-019-1204-4
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars