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Less Is More: Coarse-Grained Integrative Modeling of Large Biomolecular Assemblies with HADDOCK

[Image: see text] Predicting the 3D structure of protein interactions remains a challenge in the field of computational structural biology. This is in part due to difficulties in sampling the complex energy landscape of multiple interacting flexible polypeptide chains. Coarse-graining approaches, wh...

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Detalhes bibliográficos
Publicado no:J Chem Theory Comput
Main Authors: Roel-Touris, Jorge, Don, Charleen G., V. Honorato, Rodrigo, Rodrigues, João P. G. L. M., Bonvin, Alexandre M. J. J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2019
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6854652/
https://ncbi.nlm.nih.gov/pubmed/31539250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jctc.9b00310
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