Helper-Dependent Adenovirus Transduces the Human and Rat Retina but Elicits an Inflammatory Reaction When Delivered Subretinally in Rats

The identification of >100 genes causing inherited retinal degeneration and the promising results of recent gene augmentation trials have led to an increase in the number of studies investigating the preclinical efficacy of viral-mediated gene transfer. Despite success using adeno-associated viru...

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Detalhes bibliográficos
Publicado no:Hum Gene Ther
Main Authors: Han, Ian C., Burnight, Erin R., Ulferts, Mallory J., Worthington, Kristan S., Russell, Stephen R., Sohn, Elliott H., Mullins, Robert F., Stone, Edwin M., Tucker, Budd A., Wiley, Luke A.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc., publishers 2019
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6854516/
https://ncbi.nlm.nih.gov/pubmed/31456426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2019.159
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