Helper-Dependent Adenovirus Transduces the Human and Rat Retina but Elicits an Inflammatory Reaction When Delivered Subretinally in Rats

The identification of >100 genes causing inherited retinal degeneration and the promising results of recent gene augmentation trials have led to an increase in the number of studies investigating the preclinical efficacy of viral-mediated gene transfer. Despite success using adeno-associated viru...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Hum Gene Ther
Main Authors: Han, Ian C., Burnight, Erin R., Ulferts, Mallory J., Worthington, Kristan S., Russell, Stephen R., Sohn, Elliott H., Mullins, Robert F., Stone, Edwin M., Tucker, Budd A., Wiley, Luke A.
Format: Artigo
Jezik:Inglês
Izdano: Mary Ann Liebert, Inc., publishers 2019
Teme:
Research Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6854516/
https://ncbi.nlm.nih.gov/pubmed/31456426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2019.159
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