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Comprehensive Mutagenesis of Herpes Simplex Virus 1 Genome Identifies UL42 as an Inhibitor of Type I Interferon Induction

In spite of several decades of research focused on understanding the biology of human herpes simplex virus 1 (HSV-1), no tool has been developed to study its genome in a high-throughput fashion. Here, we describe the creation of a transposon insertion mutant library of the HSV-1 genome. Using this t...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Chapon, Maxime, Parvatiyar, Kislay, Aliyari, Saba Roghiyh, Zhao, Jeffrey S., Cheng, Genhong
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6854482/
https://ncbi.nlm.nih.gov/pubmed/31511375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01446-19
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