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The inhibition of Bax activation-induced apoptosis by RasGRP2 via R-Ras-PI3K-Akt signaling pathway in the endothelial cells

Apoptosis of endothelial cells is a very important event in various diseases and angiogenesis. We recently reported that ras guanyl nucleotide releasing protein 2 (RasGRP2), which is a guanine nucleotide exchange factor, was expressed in the human umbilical vein endothelial cells (HUVECs) and that R...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Takino, Jun-ichi, Sato, Takuma, Nagamine, Kentaro, Hori, Takamitsu
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6854084/
https://ncbi.nlm.nih.gov/pubmed/31723205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-53419-4
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