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Comparative muscle irritation and pharmacokinetics of florfenicol-hydroxypropyl-β-cyclodextrin inclusion complex freeze-dried powder injection and florfenicol commercial injection in beagle dogs

Florfenicol (FF) is a novel animal-specific amidohydrin broad-spectrum antibiotic. However, its aqueous solubility is extremely poor, far below the effective dose required for veterinary clinic. Thus, FF is often used in large doses, which significantly limits its preparation and application. To ove...

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שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Sci Rep
Main Authors: Fan, Guoqing, Zhang, Li, Shen, Yun, Shu, Gang, Yuan, Zhixiang, Lin, Juchun, Zhang, Wei, Peng, Guangneng, Zhong, Zhijun, Yin, Lizi, Fu, Hualin
פורמט: Artigo
שפה:Inglês
יצא לאור: Nature Publishing Group UK 2019
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC6853948/
https://ncbi.nlm.nih.gov/pubmed/31723173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-53304-0
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