Tumor necrosis factor induces rapid down-regulation of TXNIP in human T cells

In addition to antigen-driven signals, T cells need co-stimulatory signals for robust activation. Several receptors, including members of the tumor necrosis factor receptor superfamily (TNFRSF), can deliver co-stimulatory signals to T cells. Thioredoxin interacting protein (TXNIP) is an important in...

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Vydáno v:Sci Rep
Hlavní autoři: Levring, Trine B., Kongsbak-Wismann, Martin, Rode, Anna K. O., Al-Jaberi, Fatima A. H., Lopez, Daniel V., Met, Özcan, Woetmann, Anders, Bonefeld, Charlotte M., Ødum, Niels, Geisler, Carsten
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6853882/
https://ncbi.nlm.nih.gov/pubmed/31723203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-53234-x
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