Elevated expression of G3BP1 associates with YB1 and p‐AKT and predicts poor prognosis in nonsmall cell lung cancer patients after surgical resection

PURPOSE: G3BP1 is an RNA‐binding protein and plays roles in regulating signaling pathway. YB‐1 is a DNA/RNA binding protein encoded by YBX1 gene. Phosphorylated AKT (p‐AKT) acts as a pivotal molecule in PI3K/AKT pathway. YB‐1 drives stress granules (SGs) formation by activating G3BP1 translation und...

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Detalhes bibliográficos
Publicado no:Cancer Med
Main Authors: Zheng, Hongmei, Zhan, Yuting, Zhang, Yuting, Liu, Sile, Lu, Junmi, yang, Yang, Wen, Qiuyuan, Fan, Songqing
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Clinical Cancer Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6853815/
https://ncbi.nlm.nih.gov/pubmed/31560169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.2579
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