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Genome-wide identification of short 2′,3′-cyclic phosphate-containing RNAs and their regulation in aging
RNA molecules generated by ribonuclease cleavage sometimes harbor a 2′,3′-cyclic phosphate (cP) at their 3′-ends. Those cP-containing RNAs (cP-RNAs) form a hidden layer of transcriptome because standard RNA-seq cannot capture them as a result of cP’s prevention of an adapter ligation reaction. Here...
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| Published in: | PLoS Genet |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Public Library of Science
2019
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6853296/ https://ncbi.nlm.nih.gov/pubmed/31721758 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1008469 |
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